7.27 Principles of Human Disease

As taught in: Spring 2006

Illustration of a gene undergoing gene therapy.

Gene therapy using an adenovirus vector. Image courtesy of theĀ U.S. National Library of Medicine.




Prof. David Housman

Prof. Jacqueline Lees

Course Description

This course covers current understanding of, and modern approaches to human disease, emphasizing the molecular and cellular basis of both genetic disease and cancer. Topics include: The Genetics of Simple and Complex Traits; Karyotypic Analysis and Positional Cloning; Genetic Diagnosis; The Roles of Oncogenes and Tumor Suppressors in Tumor Initiation, Progression, and Treatment; The Interaction between Genetics and Environment; Animal Models of Human Disease; Cancer; and Conventional and Gene Therapy Treatment Strategies.